Benzofuran and indole synthesis via Cu(I)-catalyzed coupling of N-tosylhydrazone and o-hydroxy or o-amino phenylacetylene.
نویسندگان
چکیده
A general and practical method to synthesize 2-substituted benzofurans and indoles is described. This method employs easily accessible N-tosylhydrazones and o-hydroxy or o-amino phenylacetylenes as substrates. The reaction proceeds through a CuBr-catalyzed coupling-allenylation-cyclization sequence under ligand-free conditions.
منابع مشابه
Synthesis and Characterization of Some Lanthanide(III) Chloro Complexes Derived from 4[N-(4’-Hydroxy-3’-Methoxybenzalidene) Amino] Antipyrine Semicarbazone and 4[N-(3’,4’,5’-Trimethoxybenzalidene) Amino]Antipyrine Semicarbazone
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 11 9 شماره
صفحات -
تاریخ انتشار 2013